Dr. Patricia Jones, right, and Hayley McLean, master of science in public health student and Dr. Jones’ graduate research assistant.

Liver Cancer Disparities: A Complicated Picture


Hepatocellular carcinoma, the most common type of liver cancer, is a critical health problem in the United States and the fifth leading cause of cancer deaths. However, the disease does not affect all groups equally and nobody is really sure why.

Sylvester Survivorship Celebration on August 3, 2019 at Marlins Park.

Helping Cancer Survivors in Transition


Cancer survivors in the U.S. currently number 17 million, with that number expected to climb to 26 million within the next 20 years. As defined by the National Cancer Institute, cancer survivorship care focuses on the health and life of a person following initial treatment through the end of life. It covers the physical, psychosocial, and economic issues of cancer, beyond the diagnosis and initial treatment phases.

Dr. Tan Ince

HDAC7 Gene Plays a Critical Role in Breast Cancer Stem Cells


In a study recently published in the journal Oncogene, a research team led by Tan Ince, M.D., Ph.D., described the mechanisms that help the gene histone deacetylase (HDAC) 7 control other genes, driving breast cancer and helping maintain cancer stem cells. In addition, the paper showed HDAC7 activity is downstream from other HDAC molecules, particularly HDAC1, possibly making it a better therapeutic target for future

Standing, from left: President Julio Frenk, Edward Abraham, M.D., Annette de la Renta, and Henri R. Ford, M.D. Seated: Stephen D. Nimer, M.D.

Dr. Stephen D. Nimer Honored with Endowed Chair


Dr. Stephen D. Nimer, director of Sylvester Comprehensive Cancer Center, which recently received a prestigious designation from the National Cancer Institute, has been named the inaugural holder of the Oscar de la Renta Endowed Chair in Cancer Research.

Dr. Stephen D. Nimer in the lab.

Sylvester Research Identifies Novel Vulnerability in Acute Leukemia Cells


Researchers at the NCI-designated Sylvester Comprehensive Cancer Center, working within several departments at the University of Miami Miller School of Medicine, have identified another critical component of the AML1-ETO multi-protein complex that could point the way to more effective therapies for acute myeloid leukemia (AML).

Sylvester Researchers Find PARP Inhibitors Could Be a New Treatment for a Common Lymphoma


A study looking at PARP inhibition in diffuse large B cell lymphoma opens the door to a new way to treat this common type of cancer, according to study author Izidore S. Lossos, M.D., endowed director of the Lymphoma Program at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, and head of the Hematological Malignancies Site Disease Group.

A pathology slide of alveolar soft-part sarcoma.

A Paradigm Shift for Hard-to-Treat Sarcomas


Two recent studies by Sylvester Comprehensive Cancer Center researchers are the first to suggest that immunotherapy plays a key role in treating sarcomas, namely angiosarcoma and alveolar soft-part sarcoma. The findings could change the treatment paradigm for sarcoma types that have few if any treatment options.

Graduate student Marie E. Maloof, left, with Dr.  Nagi Ayad

Researcher Identifies Potential Target for Treating Aggressive Brain Tumors in Children


A researcher at Sylvester Comprehensive Cancer Center of the University of Miami Miller School of Medicine has identified a potential target for halting the unchecked cell division in medulloblastoma, the most common pediatric brain tumor. However, laboratory studies indicate that inhibiting cellular division must be done carefully during a relatively narrow window of time to avoid damage to a child’s still-developing brain.

From left, Alfred Sanchez, president of the Greater Miami Chamber of Commerce, Dr. Stephen D. Nimer, and Felipe F. Basulto, chair of the Greater Miami Chamber.

Sylvester Receives Trailblazer Award from Miami Chamber


The Mary Brickell Trailblazer Award, named after one of Miami’s founders, is given by the Greater Miami Chamber of Commerce to those at the forefront of achieving something significant, a leader in their field. On August 7 that award was presented to Director Stephen D. Nimer, M.D., on behalf of Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine.

From left, Sabita Roy, Ph.D., with first author Li Zhang, M.S.

Researchers Find Probiotics Can Reduce Morphine Tolerance in Mice


A group of researchers from Sylvester Comprehensive Cancer Center, the Department of Surgery and the Department of Medicine at the University of Miami Miller School of Medicine have found that probiotics can reduce morphine tolerance when used as an adjunct therapy in germ-free mice.

Sulagna Banerjee, Ph.D., left, with research assistant Nikita Sharma.

Two Sylvester Pancreatic Cancer Researchers Awarded Grants


Cigarette smoking is one of the major risk factors for pancreatic cancer and a focus of study for Sylvester Comprehensive Cancer Center researchers Vikas Dudeja, M.D., and Sulagna Banerjee, Ph.D. Their individual research projects, recently awarded state funding, examine different tobacco-related mechanisms that promote or drive this aggressive cancer.

David S. Kushner, M.D.

Dr. David Kushner Named Medical Director of Credentialing and Privileging


David S. Kushner, M.D., clinical professor of physical medicine and rehabilitation, has been named medical director of credentialing and privileging for the University of Miami Medical Group and the University of Miami Hospital and Clinics. He will have the responsibility for ensuring that threshold qualifications are met and continuously maintained by all applicants for appointment, reappointment, or clinical privileges.

Shivank Bhatia, M.D.

Dr. Shivank Bhatia Named Chair of Interventional Radiology


Shivank Bhatia, M.D., a member of Sylvester Comprehensive Cancer Center and associate professor of interventional radiology, has been named chair of the Department of Interventional Radiology at the University of Miami Miller School of Medicine. Dr. Bhatia has been responsible for many multidisciplinary initiatives that have moved a number of advanced clinical treatments forward.

From left, Hsuan-Ting (Emily) Huang, Ph.D., Maria Figueroa, M.D., first author Emmalee Adelman, Ph.D., and Alejandro Roisman, Ph.D., in front of the whiteboard on which they brainstormed the research project.

Epigenetic Changes May Explain How Aging Increases Blood Cancer Risks


It is widely known that aging is the single biggest non-modifiable risk factor for cancer. Now, a new study conducted by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine sheds new light on the factors associated with cellular aging and cancer risk.

From left, Chuan Chen, graduate student, No Ma, Ph.D., assistant scientist, Stephen D. Nimer, M.D., Sylvester director, and Gloria Mas-Martin, Ph.D., associate scientist, at poster display.

Sylvester Retreat Focuses on Research Progress and Future Goals


Sylvester Comprehensive Cancer Center of the University of Miami Miller School of Medicine has seen dramatic growth in its research programs over the past five years, thanks to its dedicated scientific, clinical and administrative team. At the center of all the efforts are patients.

From left, Julie Santana, David J. Arnold, M.D., and Christina Santana.

‘Lourdes’ Angels’ Donate Writing Tablets


Recently, the Santana family, calling themselves “Lourdes’ Angels,” donated 40 writing tablets to surgeon David J. Arnold, M.D., a member of Sylvester Comprehensive Cancer Center, associate professor of otolaryngology, chief of surgery at The Lennar Foundation Medical Center, and chief of head and neck surgery at UHealth Tower.

A group of riders sets off on their route.

Dolphins Cancer Challenge Attracts Thousands to Ride, Run, and Walk to Support Sylvester


For Sandy Grossman, cancer runs in the family — and so does supporting cancer research. It’s a story that could be told by many families among the thousands who turned out on April 6 to support Sylvester Comprehensive Cancer Center at the Dolphins Cancer Challenge IX at Hard Rock Stadium. The event consists of several bike rides and a 5K run/walk. All of the money raised goes to support cancer research at Sylvester.

From left, Stuart Miller, David Roth, M.D., Alessia Fornoni, M.D., Ph.D., Emmanuel Thomas, M.D., Ph.D., and Gaetano Ciancio, M.D., M.B.A.

Iron Arrow Taps Stuart Miller and Eight Medical Campus Faculty, Alumni and Students


The first indication that something is afoot is the sound of a slow-beating drum moving across campus. When the source of the sound comes into view, you see that the drummer is accompanied by a group of individuals wearing colorful jackets and marching slowly, solemnly in line. For those in the know, the big question is: Who are they looking for this time?

Brian M. Slomovitz, M.D.

Sylvester Researcher Reports Early, Promising Results of New Therapy in Several Cancers


The first study in humans to explore the potential of a new treatment for solid tumors shows acceptable safety, an effective dose range and — although not designed to do so — demonstrates that tisotumab vedotin can shrink tumors in patients with advanced or metastatic bladder, prostate, ovarian and other cancers, researchers report.

Register Now for SunSmart 5K on Sunday, March 10


Thursday, March 7, at 4 p.m., is the deadline for pre-registration for early race-packet pickup for the 10th annual SunSmart 5K (3.1 miles) run/walk, which will be held on Sunday, March 10, at 7:30 a.m., in Bill Baggs Park on Key Biscayne. It will celebrate skin and heart health by supporting skin cancer research and helping to make AEDs available in public and private places in Miami.

Miller School of Medicine Sets New Record in NIH Research Grant Funding


The University of Miami Miller School of Medicine received a record $133.5 million in research grants from the National Institutes of Health in Federal Fiscal Year 2018 — a $12.8 million increase over the school’s FFY 2017 total, raising the school another point to No. 40 of 147 institutions in the national rankings.

From left, Henri R. Ford, M.D., MHA, Emmanuel Thomas, M.D., Ph.D., and CTSI Director Ralph L. Sacco, M.D., MS.

Dean Henri R. Ford Launches Interdisciplinary Research Lecture Series


Emmanuel Thomas, M.D., Ph.D., a researcher at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, was the inaugural speaker in Dean Henri R. Ford’s Interdisciplinary Research Lecture Series. Dr. Thomas’s lecture was titled “An Integrated, Multidisciplinary Approach for the Prevention and Early Detection of Viral Hepatitis-induced Hepatocellular Carcinoma.”