Hepatocellular carcinoma, the most common type of liver cancer, is a critical health problem in the United States and the fifth leading cause of cancer deaths. However, the disease does not affect all groups equally and nobody is really sure why.
Cancer survivors in the U.S. currently number 17 million, with that number expected to climb to 26 million within the next 20 years. As defined by the National Cancer Institute, cancer survivorship care focuses on the health and life of a person following initial treatment through the end of life. It covers the physical, psychosocial, and economic issues of cancer, beyond the diagnosis and initial treatment phases.
Urologic cancer experts at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine are leading a clinical trial study for patients with non-muscle invasive bladder cancer (NMIBC) that has failed previous therapy.
In a study recently published in the journal Oncogene, a research team led by Tan Ince, M.D., Ph.D., described the mechanisms that help the gene histone deacetylase (HDAC) 7 control other genes, driving breast cancer and helping maintain cancer stem cells. In addition, the paper showed HDAC7 activity is downstream from other HDAC molecules, particularly HDAC1, possibly making it a better therapeutic target for future
Four renowned oncologists who have been treating cancer patients in this region for many years are joining Sylvester Comprehensive Cancer Center, part of the University of Miami Health System, and South Florida’s only cancer center to achieve the prestigious National Cancer Institute designation.
Dr. Stephen D. Nimer, director of Sylvester Comprehensive Cancer Center, which recently received a prestigious designation from the National Cancer Institute, has been named the inaugural holder of the Oscar de la Renta Endowed Chair in Cancer Research.
Immune therapy has not worked well in pancreatic cancer because of the cancer’s inherent immune resistance. Sylvester Comprehensive Cancer Center scientists have discovered a way to outsmart the deadly cancer’s ability to prevent immune checkpoint inhibitor therapy from killing pancreatic cancer cells.
Researchers at the NCI-designated Sylvester Comprehensive Cancer Center, working within several departments at the University of Miami Miller School of Medicine, have identified another critical component of the AML1-ETO multi-protein complex that could point the way to more effective therapies for acute myeloid leukemia (AML).
A study looking at PARP inhibition in diffuse large B cell lymphoma opens the door to a new way to treat this common type of cancer, according to study author Izidore S. Lossos, M.D., endowed director of the Lymphoma Program at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, and head of the Hematological Malignancies Site Disease Group.
Researchers have struggled with the challenge of getting oral medications past the treacherous environment of the gut intact and into the bloodstream where they can be most effective. But now Sylvester Comprehensive Cancer Center and University of Miami Miller School of Medicine researchers report success in accomplishing this breakthrough using nanotechnology.
Two recent studies by Sylvester Comprehensive Cancer Center researchers are the first to suggest that immunotherapy plays a key role in treating sarcomas, namely angiosarcoma and alveolar soft-part sarcoma. The findings could change the treatment paradigm for sarcoma types that have few if any treatment options.
A researcher at Sylvester Comprehensive Cancer Center of the University of Miami Miller School of Medicine has identified a potential target for halting the unchecked cell division in medulloblastoma, the most common pediatric brain tumor. However, laboratory studies indicate that inhibiting cellular division must be done carefully during a relatively narrow window of time to avoid damage to a child’s still-developing brain.
The Mary Brickell Trailblazer Award, named after one of Miami’s founders, is given by the Greater Miami Chamber of Commerce to those at the forefront of achieving something significant, a leader in their field. On August 7 that award was presented to Director Stephen D. Nimer, M.D., on behalf of Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine.
Sylvester Comprehensive Cancer Center, part of the University of Miami Leonard M. Miller School of Medicine, has received the prestigious NCI designation from the National Cancer Institute.
The Florida Cancer Data System, located at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, recently received three important distinctions for the quality of its cancer registry data.
A group of researchers from Sylvester Comprehensive Cancer Center, the Department of Surgery and the Department of Medicine at the University of Miami Miller School of Medicine have found that probiotics can reduce morphine tolerance when used as an adjunct therapy in germ-free mice.
Cigarette smoking is one of the major risk factors for pancreatic cancer and a focus of study for Sylvester Comprehensive Cancer Center researchers Vikas Dudeja, M.D., and Sulagna Banerjee, Ph.D. Their individual research projects, recently awarded state funding, examine different tobacco-related mechanisms that promote or drive this aggressive cancer.
David S. Kushner, M.D., clinical professor of physical medicine and rehabilitation, has been named medical director of credentialing and privileging for the University of Miami Medical Group and the University of Miami Hospital and Clinics. He will have the responsibility for ensuring that threshold qualifications are met and continuously maintained by all applicants for appointment, reappointment, or clinical privileges.
Shivank Bhatia, M.D., a member of Sylvester Comprehensive Cancer Center and associate professor of interventional radiology, has been named chair of the Department of Interventional Radiology at the University of Miami Miller School of Medicine. Dr. Bhatia has been responsible for many multidisciplinary initiatives that have moved a number of advanced clinical treatments forward.
It is widely known that aging is the single biggest non-modifiable risk factor for cancer. Now, a new study conducted by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine sheds new light on the factors associated with cellular aging and cancer risk.
Sylvester Comprehensive Cancer Center of the University of Miami Miller School of Medicine has seen dramatic growth in its research programs over the past five years, thanks to its dedicated scientific, clinical and administrative team. At the center of all the efforts are patients.
Seven faculty members at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine received awards of recognition at this year’s Zubrod Memorial Lecture.
A 31-year-old woman with sickle cell disease who had suffered with crippling pain all her life now shows no sign of the disease after being treated at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine.
Recently, the Santana family, calling themselves “Lourdes’ Angels,” donated 40 writing tablets to surgeon David J. Arnold, M.D., a member of Sylvester Comprehensive Cancer Center, associate professor of otolaryngology, chief of surgery at The Lennar Foundation Medical Center, and chief of head and neck surgery at UHealth Tower.
For Sandy Grossman, cancer runs in the family — and so does supporting cancer research. It’s a story that could be told by many families among the thousands who turned out on April 6 to support Sylvester Comprehensive Cancer Center at the Dolphins Cancer Challenge IX at Hard Rock Stadium. The event consists of several bike rides and a 5K run/walk. All of the money raised goes to support cancer research at Sylvester.
The first indication that something is afoot is the sound of a slow-beating drum moving across campus. When the source of the sound comes into view, you see that the drummer is accompanied by a group of individuals wearing colorful jackets and marching slowly, solemnly in line. For those in the know, the big question is: Who are they looking for this time?
Social workers across the University of Miami Heath System tend to be selfless in their day-to-day support and education of patients, families and colleagues on their interdisciplinary teams. The celebration of Social Work Month each March, however, provides an opportunity to step back and acknowledge their essential roles in patient care.
The first study in humans to explore the potential of a new treatment for solid tumors shows acceptable safety, an effective dose range and — although not designed to do so — demonstrates that tisotumab vedotin can shrink tumors in patients with advanced or metastatic bladder, prostate, ovarian and other cancers, researchers report.
Thursday, March 7, at 4 p.m., is the deadline for pre-registration for early race-packet pickup for the 10th annual SunSmart 5K (3.1 miles) run/walk, which will be held on Sunday, March 10, at 7:30 a.m., in Bill Baggs Park on Key Biscayne. It will celebrate skin and heart health by supporting skin cancer research and helping to make AEDs available in public and private places in Miami.
The University of Miami Miller School of Medicine received a record $133.5 million in research grants from the National Institutes of Health in Federal Fiscal Year 2018 — a $12.8 million increase over the school’s FFY 2017 total, raising the school another point to No. 40 of 147 institutions in the national rankings.
Emmanuel Thomas, M.D., Ph.D., a researcher at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, was the inaugural speaker in Dean Henri R. Ford’s Interdisciplinary Research Lecture Series. Dr. Thomas’s lecture was titled “An Integrated, Multidisciplinary Approach for the Prevention and Early Detection of Viral Hepatitis-induced Hepatocellular Carcinoma.”