News

Soumya Sundara Rajan, Ph.D., MSc, in the laboratory.

Novel Use of CRISPR for Cancer Research at Sylvester

12.20.2018

In Dr. Jonathan Schatz’s laboratory at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, researchers have pioneered a new use for CRISPR, the genomic editing tool at the center of much media attention.

At the Micah Batchelor Awards ceremony, from left, Henri R. Ford, M.D, MHA, Brent Pfeiffer, M.D., Ph.D., Merline Benny, M.D., Juan Solano, M.D., Asha Pillai, M.D., Judy Schaechter, M.D., MBA, and President Julio Frenk.

Four Researchers Honored by the Batchelor Foundation

12.14.2018

The 14th presentation of the Micah Batchelor Awards for Excellence in Children’s Health Research, created to recognize and inspire the development of innovative ideas and solutions to improve the health and well-being of children, took place November 8. Four researchers from Sylvester Comprehensive Cancer Center and the Department of Pediatrics at the University of Miami Miller School of Medicine were honored at the ceremony.

From left, Himanshu Arora, Ph.D., with Ranjith Ramasamy, M.D.

Sylvester Researchers Show Nitric Oxide Suppresses Drug-Resistant Prostate Cancer

10.15.2018

Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have shown in animal models that S-nitrosoglutathione (GSNO), a compound that increases nitric oxide (NO) levels, suppresses castration-resistant prostate cancer and has a major impact on tumor microenvironments. The discovery could lead to new therapies for prostate cancer patients with few options.

Carmen Calfa, M.D., right, talks to TAPUR Study participant Anita Shangvi and her daughter.

Sylvester is Sole Florida Site for TAPUR Study

09.26.2018

TAPUR — Targeted Agent and Profiling Utilization Registry — is for patients with advanced solid tumors in a variety of cancers, including breast, ovarian, pancreatic, and head and neck, which are no longer responding to standard cancer treatments.

Sylvester Comprehensive Cancer Center.

Florida Cancer Data System at Sylvester is Again Recognized as One of the Best in the U.S.

09.14.2018

The Florida Cancer Data System, the State of Florida’s legislatively mandated population-based registry located at Sylvester Comprehensive Cancer Center, has received three important distinctions for the quality of its cancer registry data. For the 16th consecutive year, the Florida Cancer Data System (FCDS) has received Gold Certification from the North American Association of Central Cancer Registries.

Sylvester Researchers Focus on an Interesting Target: PRMT5

09.04.2018

Cancer researchers spend a lot of time looking for good targets: potentially druggable molecules (mostly proteins) that affect cancer progression. The laboratory of Stephen D. Nimer, M.D., director of Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, has spent the past decade investigating an enzyme called PRMT5, which plays a role in leukemia, lymphoma and other cancers.

Sylvester Researchers Discover A Novel Mediator of Genome Instability Relevant to Many Cancers

08.27.2018

A research team at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine has discovered a novel role for a protein factor that allows it to contribute to the genome instability observed in many cancer cells. The investigators found that the FANCA protein plays an unexpected role in an error-prone DNA repair pathway that can drive the common instability mechanism.

CTSI Leadership and Central Operations Team: from left, top row, Patricia Avissar, Caprice Battle, Marisabel Davalos, Jonelle Wright, Ph.D., Sheela Dominguez and Stella Covelli; from left, bottom row, Rosalina Das, Raquel Perez, Dushyantha Jayaweera, M.D., Ralph L. Sacco, M.D., M.S., Daru Lane Ransford and Chin Chin Lee.

Major NIH Award Makes Miami CTSI a Hub for Biomedical Discovery and Innovation

08.24.2018

The Miami Clinical and Translational Science Institute has received a five-year $21.5 million National Institutes of Health grant, which will be supplemented by the Miller School of Medicine and the University of Miami Office of the Provost, to fund collaborative research to speed the discovery of new medical treatments and cures.

A photographic image showing a retinoblastoma.

Researchers Receive Grant to Study Retinoblastoma in Children

08.23.2018

J. William Harbour, M.D., and Daniel Pelaez, M.D., researchers at Sylvester Comprehensive Cancer Center and Bascom Palmer Eye Institute at the University of Miami Miller School of Medicine, have been awarded a $250,000 grant by Alex’s Lemonade Stand Foundation for their 2018 Innovation Grant application titled “Molecular Landscape for Targeted Therapy in Retinoblastoma.”

Study collaborators, from left: Haley Perlow, Miller School medical student; Laura Huang M.D., physical medicine and rehabilitation specialist; Stuart Samuels, M.D., Ph.D., principal investigator; Diana Molinares, M.D., physical medicine and rehabilitation resident; and Gregory Azzam, M.D., Ph.D., radiation oncology resident.

Sylvester Researcher Receives Grant to Study Long-Term Side Effects of Head and Neck Radiotherapy

08.15.2018

Radiation therapy can be an effective treatment for people diagnosed with head and neck cancer. However, weeks, months or years after treatment, a debilitating side effect — fibrosis of the skin, subcutaneous tissue and muscles of the neck — often arises. This excess production of fibrous connective tissue and scarring can significantly decrease patient quality of life and limit physical function.

Doyoung Chang, Ph.D., in his laboratory.

Robotics Lab Opens for Business

08.01.2018

Not long ago, Doyoung Chang, Ph.D., was designing robots that may be climbing — and cleaning — the walls of skyscrapers one day. Now the biomechanical engineer is intent on perfecting a robotic arm that helps cancer fighters at Sylvester Comprehensive Cancer Center and across the University of Miami Health System obliterate small tumors with a heat-delivering needle inserted through the skin.

Dr. Enrique A. Mesri, left, and Dr. Julian Naipauer in the lab.

Researcher Identifies Viral Activation Pathway, Pointing Toward Therapies for AIDS-Kaposi Sarcoma

07.23.2018

A Sylvester Comprehensive Cancer Center viral oncology researcher has discovered a key cellular pathway associated with activating Kaposi sarcoma, a rare cancer most often found in people with HIV/AIDS or otherwise compromised immune systems. “We have identified the main oncogenic driver of the tumor and the viral mechanism of activation,” said lead author Enrique A. Mesri, Ph.D.

Sylvester's sarcoma team, including, from right, Jonathan Trent, M.D., Ph.D., patient Ron Agypt, and Breelyn Wilky, M.D.

Sylvester Named GIST Center of Excellence by The Life Raft Group

07.19.2018

Sarcoma specialist Jonathan Trent, M.D., Ph.D., and his team, including Breelyn Wilky, M.D., received the first GIST Center of Excellence award on behalf of Sylvester Comprehensive Cancer Center from The Life Raft Group on July 14 during Life Fest 2018, a weekend conference for patients, caregivers and medical experts.

Researchers compared disparities in cancer risk and mortality among diverse populations in New York with those found in Florida in earlier studies.

Distinct Racial and Ethnic Differences in Cancer Mortality Revealed in Published Study

07.19.2018

Expanding on previous work highlighting disparities in cancer risk and mortality among diverse populations in Florida, a research team from Sylvester Comprehensive Cancer Center analyzed almost 250,000 people who died from cancer between 2008 and 2014 in another state with a diverse population: New York. Results of this new study were published on July 19 in the journal Cancer Epidemiology, Biomarkers & Prevention.

Brian M. Slomovitz, M.D.

Sylvester is One of Four Sites for Clinical Trial to Treat Advanced Colorectal and Ovarian Cancers

07.13.2018

Brian M. Slomovitz, M.D., director of the Division of Gynecologic Oncology at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, is overseeing a Phase I/II study of a combination therapy to treat advanced colorectal and ovarian cancers. Sylvester is one of only four sites in the U.S. participating in the multicenter trial, and is the only site in Florida.

Sylvester radiation oncology team with colleagues in the Dominican Republic.

Sylvester Radiation Oncologists Travel to Dominican Republic for Consulting Engagement

07.12.2018

A group of radiation oncologists from Sylvester Comprehensive Cancer Center recently traveled to the Dominican Republic for a hands-on consulting engagement at Instituto Oncologico Heriberto Pieter in Santo Domingo. The cancer specialists made the trip to as part of the memorandum of understanding signed a year ago with the institute’s medical director, Jose Ramirez, M.D.

From left, Jennifer Jehn, Dr. Stephen Nimer, Dr. Sara St. George, Lesley Visser, Twan Russell and Keith Goralski at the grant announcement.

Sylvester Researcher Receives Grant to Help Female Cancer Survivors

07.11.2018

Sara Mijares St. George, Ph.D., of Sylvester Comprehensive Cancer Center, has received a $200,000 grant from the V Foundation for Cancer Research, founded by ESPN and Jim Valvano, through a collaboration with the Dolphins Cancer Challenge. The grant will fund a study that will provide information to Hispanic and black female cancer survivors to improve weight, physical activity and nutrition.

Nurse practitioners Amanda Chaney, left, and Jessica MacIntyre, right, receive their awards from Jacinto Garrido, Ph.D., DNP, South Florida’s state representative to the American Association of Nurse Practitioners.

Sylvester Nurse Practitioner Honored for Advocacy

07.09.2018

Jessica MacIntyre, M.S.N., ARNP, director of clinical operations at Sylvester Comprehensive Cancer Center, has been honored by the American Association of Nurse Practitioners (AANP) for her advocacy on behalf of Florida’s nurse practitioners. MacIntyre, who is co-director of Florida’s only oncology fellowship program developed for nurse practitioners, received the 2018 AANP State Award for Nurse Practitioner Advocacy.

Frank J. Penedo, Ph.D.

Cancer Survivorship Expert Dr. Frank J. Penedo Joins Sylvester

07.05.2018

Frank J. Penedo, Ph.D., an internationally recognized expert in cancer survivorship and psychosocial oncology, will join Sylvester Comprehensive Cancer Center on August 15 as associate director for cancer survivorship and translational behavioral research. Dr. Penedo will also co-lead the cancer control research program. “I am delighted to rejoin the team at Sylvester,” said Dr. Penedo.

High-power histologic image of a tumor before treatment shows central comedolike necrosis and atypical basaloid cells with mitoses.

Sylvester's Use of HPV Vaccine to Treat Patient with Skin Tumors Reported in JAMA Dermatology

07.03.2018

Two years ago, a 97-year-old woman whose right leg was covered with squamous cell tumors went to see dermatologist Anna Nichols, M.D., Ph.D., with Sylvester Comprehensive Cancer Center. Dr. Nichols injected the HPV vaccine Gardasil directly into the patient's tumors, and the tumors completely resolved. A report on the successful treatment was published online July 3 in _JAMA Dermatology_.

Poster winners, from left, Lauren Gjolaj, Lauren Gallegos, B.S.N., RN, Angela Olier-Pino, M.B.A., D.N.P., ARNP, Julia Khalil, Pharm.D., Rohanmi Perez, B.S.N., RN, Gloria Campos, Denise Perez, B.S.N., RN.

Sylvester Team is Florida Sterling Showcase Champion

06.22.2018

A multidisciplinary and talented team from Sylvester Comprehensive Cancer Center presented a project called “Letting Go” of Denied Charges to Build a Lean Healthcare System at the 26th Annual Florida Sterling Conference, took home the top team prize, and patients are benefiting from their work. The 12-minute presentation included a song-and-dance performance with a Frozen theme.

From left, at commencement, research team leader R. Grace Zhai, Ph.D., with first author Jennifer M. Brazill, Ph.D., whose dissertation described the findings that appeared in the journal article.

Researchers Uncover Clues to Treatment for Chemotherapy-induced Peripheral Neuropathy

06.22.2018

Chemotherapy can extend life, or even provide a cure, but occasionally with side effects so severe that patients reduce or discontinue treatment. Take the case of paclitaxel, an agent originally derived from the bark of the western yew tree, and one of the most common tools used to treat cancers of the ovary, breast, lung, and head and neck.

Dr. Stephen D. Nimer and Gloria Mas Martin in the lab.

Targeting CARM1 Inhibits AML and Spares Normal Cells

06.11.2018

Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have shown that inhibiting the enzyme CARM1 (also called PRMT4) dramatically slows acute myeloid leukemia (AML) progression but does not affect normal blood production. This selectivity could make it an ideal drug target for AML – a disease with few treatment options. The study was published online June 11 in Cancer Cell.

From left, Adam Carlin, Bill Tenney, Lourdes Beltran and Dr. Stephen D. Nimer cut the ribbon.

Sylvester Honors the Woman’s Cancer Association

06.11.2018

For nearly 60 years, the Woman’s Cancer Association of the University of Miami has supported cancer research, education and patients’ needs. On June 7, the WCA was honored in a ribbon-cutting ceremony at Sylvester Comprehensive Cancer Center at The Lennar Foundation Medical Center. This special celebration marked the dedication of a patient lounge on the fourth floor that now bears the group’s name.

Dr. Gilberto Lopes, left, is interviewed by reporters at the ASCO meeting.

After ASCO 2018: Sylvester Presenter Among ‘Cream of the Crop’

06.11.2018

Journalists from Japan, Portugal and other countries lined up to interview Sylvester Comprehensive Cancer Center’s associate director of global oncology, Gilberto Lopes, M.D., MBA, outside the press room at the annual meeting of the American Society of Clinical Oncology. It was June 3, and as lead author of the Keynote-042 study, Lopes had just released the impressive results of an immunotherapy drug for lung cancer patients.

Alejandra Perez, M.D.

Dr. Alejandra Perez of Sylvester Appointed to ASCO Committee

06.04.2018

The director of Sylvester Comprehensive Cancer Center’s Braman Family Breast Cancer Institute at Plantation, Alejandra Perez, M.D., has been appointed to serve on the Clinical Practice Guidelines Committee of the American Society of Clinical Oncology. ASCO is the world’s leading professional organization for physicians and oncology professionals caring for people with cancer.

Breast cancer under light microscopy.

Sylvester Breast Cancer Specialist Publishes Commentary in New England Journal of Medicine

06.04.2018

On June 4, The New England Journal of Medicine published an update to a large, international study of two clinical trials that examined the comparative survival rates for adjuvant therapies for hormone-receptor-positive breast cancer in premenopausal women. The journal’s editors turned to Marc E. Lippman, M.D., a breast cancer specialist at Sylvester Comprehensive Cancer Center, to write an accompanying editorial.

Natasha Schaefer Solle, Ph.D., and Alberto Caban-Martinez, D.O., Ph.D., M.P.H., center, with marine firefighters from Jacksonville Fire and Rescue's Station 39.

Sylvester’s Firefighter Cancer Initiative Expands to Jacksonville Area

06.01.2018

Over the Memorial Day weekend, clinician-scientists from Sylvester Comprehensive Cancer Center’s expanding state-funded Firefighter Cancer Initiative met with firefighters and paramedics at fire rescue departments throughout the greater Jacksonville area, and presented an overview of their research and cancer screening projects.

Jessica MacIntyre, M.S.N., ARNP, helps patient Althea Chung try on one of the new hoodies.

Donated Hoodies Help Sylvester Patients and Staff by Adding Convenience and Comfort

05.29.2018

Patients at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine are the first in the country to receive new specially designed hoodies donated by Oscar de la Renta, LLC. In place of a long zipper down the middle, these hoodies have two shorter diagonal zippers that make it easier for nurses to access chemotherapy chest ports, while helping patients stay warm.

Gilberto Lopes, M.D., M.B.A.

Sylvester Physicians and Researchers to Present at ASCO

05.23.2018

Sylvester Comprehensive Cancer Center will be well represented at the 2018 American Society of Clinical Oncology (ASCO) meeting June 1- 5 in Chicago, as several physicians and researchers are scheduled to make key presentations. At the Plenary Session on Sunday, June 3, Gilberto Lopes, M.D., M.B.A., associate director of Global Oncology at Sylvester, will present the abstract on the Phase III KEYNOTE-42 study.

Asha B. Pillai, M.D.

Sylvester’s Dr. Asha B. Pillai Receives Grant for Innovative Transplant Immunology Research

05.21.2018

Asha B. Pillai, M.D., a Sylvester Comprehensive Cancer Center researcher who specializes in pediatric immunotherapy, has received a $1.5 million grant from the National Institutes of Health for her innovative work in transplant immunology. Pillai wants to give hope, and perhaps even a cure, to patients with non-cancerous blood disorders like sickle cell anemia and thalassemia.

Felicia Knaul, Ph.D., with Gilberto Lopes, M.D., M.B.A.

Sylvester Shares its Cancer Expertise to Improve Care in Other Countries

05.18.2018

Global Oncology and International Programs at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine recently established new partnerships in South America, collaborated on an international symposium in Brazil, and hosted the first annual Global Oncology Research Dialogue at Sylvester.

From left, Luis Chiappy, AXA Advisors, Mary Bartlett Bunge, Ph.D., and Chris Dudley, Advancement Associates, Inc.

UM Researcher, Transplant Surgeon and Sylvester Trustee among 2018 Health Care Heroes

05.15.2018

For nearly 30 years, Mary Bartlett Bunge, Ph.D., worked tirelessly as a neuroscientist with The Miami Project to Cure Paralysis at the University of Miami Miller School of Medicine. Her pioneering work in the area of nervous system regeneration and her decades-long dedication to finding ways to repair spinal cord damage earned Bunge the 2018 Lifetime Achievement Award from the Greater Miami Chamber of Commerce.

Craig H. Moskowitz, M.D.

Lymphoma Expert Dr. Craig Moskowitz Joins Sylvester as Physician-in-Chief for Oncology Service Line

05.11.2018

Craig H. Moskowitz, M.D., one of the world’s leading experts on lymphoma, will join Sylvester Comprehensive Cancer Center on May 14 as physician-in-chief for the Oncology Service Line. He is board certified in internal medicine, medical oncology and hematology. Additionally, he is the author of more than 275 articles in high-impact journals and a sought-after speaker at scientific conferences worldwide.

Alberto J. Caban-Martinez, right, receives his award from John M. Carethers, M.D., of the University of Michigan, the chairman of the Minorities in Cancer Research Council of the American Association for Cancer Research.

Sylvester Researcher Honored with Minority Faculty Scholar Award

05.02.2018

Sylvester Comprehensive Cancer Center researcher Alberto J. Caban-Martinez, D.O., Ph.D., M.P.H., C.P.H., has been honored for his scholarly work investigating cancer screening practices among Florida’s firefighters. Caban-Martinez received the American Association for Cancer Research (AACR) 2018 Minority Faculty Scholar in Cancer Research Award at the association’s annual meeting in Chicago.

Nearly 800 employees and faculty caught the spirit at the 5 to Thrive launch event.

5 to Thrive Comes Alive at Major Event to Generate Employee and Faculty Input

04.30.2018

Nearly 800 medical campus employees and faculty packed the tent erected on the Schoninger Research Quadrangle last Thursday afternoon, their animated conversation mixing with the DJ’s music as they celebrated the energetic launch of 5 to Thrive, a dynamic new initiative designed to make UHealth – the University of Miami Health System a truly preeminent academic health system for the 21st century.

Dr. Jonathan Trent, Bat-ami Katzman Gordon and Jared Cotta.

Sylvester Molecular Tumor Board Reaches Patient Milestone

04.27.2018

Precision medicine experts at Sylvester Comprehensive Cancer Center are applying advances in cancer genetics – specific mutations that occur across tumor types and locations – to match people to therapy that targets the mutation driving their cancer. Under the leadership of Jonathan C. Trent, M.D., Ph.D., the Molecular Tumor Board has reviewed 300 patient cases

Priyamvada Rai, Ph.D.

Dr. Priyamvada Rai of Sylvester Named to Tumor Cell Biology Study Section

04.25.2018

Sylvester Comprehensive Cancer Center researcher Priyamvada Rai, Ph.D., has been appointed to the Tumor Cell Biology Study Section of the Center for Scientific Review at the National Institutes of Health. Being named a member of the study section is a distinct honor and “a unique opportunity to contribute to the national biomedical research effort,” the director of the Center for Scientific Review said in his letter to Rai.

BC-3 cells were stained with DAPI, anti-vFLIP, anti-CADM1, and cholera toxin B conjugated with red fluorescence to detect GM-1 and subjected to confocal microscopy.

Sylvester Researchers Identify Protein that Triggers Virus-Mediated Chronic Inflammation and Cancers

04.25.2018

Viruses are linked to approximately 12 percent of all cancers and are associated with chronic inflammation. Sylvester Comprehensive Cancer Center researchers Noula Shembade, Ph.D., Richard Hunte and colleagues honed in on what activates that process. They found the human protein CADM1 interacts with Kaposi’s sarcoma viral proteins and promotes inflammation that can result in development of certain cancers.

From left, Ashok, Saluja, Ph.D., Vrishketan Sethi, M.B.B.S., and Vikas Dudeja, M.D.

A New Take on Immunotherapy: Gut Microbes and Tumor Growth

04.24.2018

Investigating the microbiome has provided new insights into infection control, metabolism and mental health. It may also play a significant and surprising role in cancer. Scientists at Sylvester Comprehensive Cancer Center have shown that depleting the gut microbiome reduces tumor growth and metastases in models of pancreatic cancer and melanoma and slows metastases in colon cancer.

From left, Jessica MacIntyre, M.S.N., ARNP, Stephen D. Nimer, M.D., Jaime R. Merchan, M.D., Dalissa Tejera, R.N., ARNP, and Yvonne Trang Dinh, CCRP.

Sylvester Opens New Clinic for Cancer Patients in Phase 1 Clinical Trials

04.24.2018

Patients who participate in Phase 1 clinical trials at Sylvester Comprehensive Cancer Center now have a new clinic where they can get their specialized care in one convenient location. On Friday, April 20, Sylvester’s director, Stephen D. Nimer, M.D., and the director of Phase 1 clinical trials, Jaime Merchan, M.D., cut the ribbon at the new clinic located on the third floor.

Kay and Jack Lombardo with Dr. Asha Pillai, right, at the Woman’s Cancer Association gala.

Dr. Asha Pillai of Sylvester Honored as ‘Cancer Researcher of the Year’

04.10.2018

A pediatric cancer researcher at Sylvester Comprehensive Cancer Center has been honored for groundbreaking immunotherapy studies. Asha Pillai, M.D., a specialist in pediatric hematology-oncology, was named “Cancer Researcher of the Year” by the Woman’s Cancer Association of the University of Miami at its “Dancing for a Cure” Gala.

From left, Karlene Popplewell, clinical assistant, Christine Chen-Shue, RN, Kimberly Delancy, LPN, Kristine Ruche, RN, Marina Rodriguez, LPN, and Barbara Young-Chang, RN.

Sylvester Team Wins Patient Safety Awareness Week Poster Contest

03.26.2018

A team from Sylvester Comprehensive Cancer Center’s Surgical Oncology Department has won the Grand Prize in UHealth’s Patient Safety Awareness Week Poster Contest. The Sylvester department’s entry was one of more than 50 submitted by teams from across the UHealth system. Entries were judged based on creativity, alignment of message, and presentation.

Brian M. Slomovitz, M.D., right, receives the 2018 SOG Presidential Award from Pamela T. Soliman, M.D., M.P.H.

Sylvester Researcher Dr. Brian Slomovitz Receives Award for Best Presentation at Conference

03.21.2018

Brian M. Slomovitz, M.D., co-leader of the Gynecologic Cancers Site Disease Group at Sylvester Comprehensive Cancer Center, received the 2018 Presidential Abstract Award from the Society for Gynecologic Oncology on March 24 during the group’s Annual Meeting on Women’s Cancer in New Orleans. The award was given to Slomovitz for his presentation, which was judged the conference’s best.

Systems Biology and Data Science Symposium attendees. Photo credit: Carlos Enchenique.

Systems Biology and Data Science Symposium Presents Cutting-Edge Advances

03.20.2018

Prominent speakers from Sylvester Comprehensive Cancer Center and other departments and centers at the University of Miami Miller School of Medicine came together with invited experts from the National Institutes of Health and other leading national scientific organizations for an interactive two-day symposium on systems biology and data science preceded by a Data Science Hackathon.

From left, Andrea Williams, Dr. Krishna Komanduri, and Harold Eugene Williams, Andrea’s husband.

Sylvester Comprehensive Cancer Center Celebrates 1,000th Stem Cell Transplant

03.19.2018

When Marcos C. Perez was diagnosed with chronic myeloid leukemia, an uncommon cancer of the blood-producing cells of the bone marrow, he began treatment at Sylvester Comprehensive Cancer Center. After three rounds of chemotherapy, Perez received stem cell transplants to rebuild the white blood cells in his immune system. "I am very positive about my outcome, because so many patients come out of Sylvester as winners."

From left, Erin Kobetz, Ph.D., M.P.H., Peter Tunney, and Stephen D. Nimer, M.D., outside the Game Changer vehicle.

Sylvester’s New Outreach Vehicle a ‘Game Changer’ for Community Cancer Care

03.05.2018

Acclaimed Miami artist Peter Tunney donated his time and talent to help Sylvester Comprehensive Cancer Center launch a “Game Changer” outreach vehicle that will bring cancer screenings and health information to underserved South Florida communities. Using images from Sylvester’s history and mission, Tunney created an original piece of art to “wrap” the mobile van, which was unveiled outside Tunney’s Wynwood studio.

2018 Patient Safety Awareness Week Schedule of Events

03.02.2018

Monday, March 12, begins UHealth’s observance of Patient Safety Awareness Week — an annual national campaign to increase awareness about patient safety among health care professionals and the public. This year’s theme is “Every Day is Patient Safety Day!” — an affirmation of our dedication to creating the safest possible environment for our patients and for each other.

Sylvester Researchers Discover New Pathway Linking Inflammation and Cancer

02.23.2018

A team of researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, collaborating with outside investigators, has discovered a new pathway of inflammation-driven cancer development. Their findings, “Initiation of Inflammatory Tumorigenesis by CTLA4 Insufficiency Due to Type 2 Cytokines,” were published online on January 26 by the Journal of Experimental Medicine.

Barbara A. Vance, Ph.D., CRA.

Dr. Barbara A. Vance to Join Sylvester as Assistant VP and Associate Director for Administration

02.20.2018

Barbara A. Vance, Ph.D., CRA, will join Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine on March 17 as assistant vice president and associate director for administration. Vance will be a senior member of Sylvester’s leadership team, responsible for efficient operations and financial performance, including submission of the National Cancer Institute (NCI) Cancer Center Support Grant.

Team members of the Sylvester Phase 1 clinical trials program.

Sylvester Provides 100 Patients Potentially Life-Saving Treatments in its Phase 1 Trial Program

02.19.2018

Dr. Jaime Merchan is thrilled that Sylvester Comprehensive Cancer Center has reached the milestone number of 100 patients enrolled in a single year in its Phase 1 clinical trials program. The program, which tests new drugs and other novel treatment strategies for advanced solid tumors and hematological malignances, offers these patients something they couldn’t find elsewhere: hope.

Sylvester Comprehensive Cancer Center.

New Analysis: Patients Receiving Chemo for Cancer at ADCC Institutions Have Highest Survival Rates

02.19.2018

Patients treated with chemotherapy for some of the most common types of cancer at Dedicated Cancer Centers have higher survival rates compared to patients treated at other types of hospitals, according to new analysis conducted by Milliman for the Alliance of Dedicated Cancer Centers. Sylvester Comprehensive Cancer Center is one of only 11 members of the Alliance of Dedicated Cancer Centers.

Sylvester Comprehensive Cancer Center.

Sylvester Again Recognized as a Cancer Center of Excellence

02.16.2018

Sylvester Comprehensive Cancer Center has once again been recognized as a Cancer Center of Excellence by the State of Florida — one of just four cancer centers in the state, and the only one in South Florida, to have earned this honor. The designation recognizes providers that exceed service standards and excel in providing quality, comprehensive and patient-centered, coordinated care for cancer patients in Florida.

Adult bone marrow transplant procedure.

Florida Blue Renews Recognition of Sylvester's Adult Bone Marrow Transplant Program

02.13.2018

Florida Blue has renewed its Blue Distinction Center for Transplants designation for the adult bone marrow transplant program at Sylvester Comprehensive Cancer Center. The renewed designation is recognition that the program at Sylvester, part of UHealth – the University of Miami Health System, continues to meet the insurer’s national standards for high quality care and outcomes.

Erin N. Kobetz, Ph.D., M.P.H., Jimmy Patronis, and Stephen D. Nimer, M.D. (from left in center), with fire department representatives.

Florida CFO Jimmy Patronis Tours Sylvester, Praises Firefighters Cancer Initiative

02.09.2018

Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine welcomed the State of Florida’s Chief Financial Officer, Jimmy Patronis, on February 5, giving him a tour of its cancer-fighting technologies. Patronis also met with representatives from more than a dozen of South Florida’s fire departments whose members are collaborating with Sylvester’s Firefighters Cancer Initiative.

From left, Alvaro J. Alencar, M.D., Edmundo Carvalho Mauad, M.D., Ph.D., Gilberto de Lima Lopes, M.D., M.B.A., Sergio Vicente Serrano, M.D., Ph.D., and Joseph D. Rosenblatt, M.D.

Sylvester and Brazil’s Barretos Cancer Hospital Sign Agreement for Collaborative Research

02.06.2018

Sylvester Comprehensive Cancer Center and Barretos Cancer Hospital — one of the most advanced public hospital cancer centers in Brazil — signed a memorandum of understanding on February 2 for wide-ranging collaborative research that may begin by the end of this year. Representatives from Barretos traveled to Miami to sign the agreement, meet with Sylvester researchers and clinicians, and tour Sylvester’s facilities.

From left, Alvaro J. Alencar, M.D., Edmundo Carvalho Mauad, M.D., Ph.D., Gilberto de Lima Lopes, M.D., M.B.A., Sergio Vicente Serrano, M.D., Ph.D., and Joseph D. Rosenblatt, M.D.

Sylvester and Brazil’s Barretos Cancer Hospital Sign Agreement for Collaborative Research

02.06.2018

Sylvester Comprehensive Cancer Center and Barretos Cancer Hospital — one of the most advanced public hospital cancer centers in Brazil — signed a memorandum of understanding on February 2 for wide-ranging collaborative research that may begin by the end of this year. Representatives from Barretos traveled to Miami to sign the agreement, meet with Sylvester researchers and clinicians, and tour Sylvester’s facilities.

Researchers discovered a direct link between G protein-coupled receptors and DNA demethylation.

Link between Environment and DNA May Have Implications for Human Health and Diseases

02.06.2018

Researchers from Sylvester Comprehensive Cancer Center, the John P. Hussman Institute for Human Genomics and The Miami Project to Cure Paralysis at the University of Miami Miller School of Medicine, in collaboration with colleagues from other institutions, have discovered a direct link between G protein-coupled receptors (GPCRs) and DNA demethylation — an important finding that could be implicated in human health and diseases.

Felicia Marie Knaul, Ph.D., making her grand rounds presentation.

Dr. Felicia Marie Knaul Addresses Global Women's Cancer Disparities

02.02.2018

Felicia Marie Knaul, Ph.D., a member of Sylvester Comprehensive Cancer Center, professor of public health sciences and director of the University of Miami Institute for Advanced Study of the Americas, described the challenges of global women’s cancer disparities in a grand rounds presentation Jan. 31, part of a lecture series presented by Sylvester’s Global Oncology and International Programs.

Cancer cells.

Going Global to Prevent and Treat Cancer

02.01.2018

“You have cancer” are three of the most frightening words anyone can hear. Your situation is especially perilous if you live in Asia, Africa, Central or South America. According to the World Health Organization, about 60 percent of new cancer cases and 70 percent of cancer deaths occur in those regions. The statistics hit close to home for Gilberto de Lima Lopes Jr., M.D., at Sylvester Comprehensive Cancer Center.

Omar Nelson, Ph.D., running in the Fitbit Miami Marathon.

Sylvester Researcher Runs to Fight Cancer and Bring Communities Together

01.30.2018

Omar Nelson, Ph.D., was giving it his all — “you always save something for the end” — as he crossed the finish line at the Fitbit Miami Marathon on Sunday, January 28. Still, he had good reason to be tired. He had not only completed the grueling 26.2-mile run, but also the 13.1-mile half marathon earlier in the morning — 39.3 miles total. He was the first person ever to run both races back to back.

From left, Enrique A. Mesri, Ph.D., Consul General Marcelo Martin Giusto, Edward Abraham, M.D., and Stephen D. Nimer, M.D.

Argentina Consulate Celebrates Research Collaboration with Sylvester and CFAR

01.24.2018

The Consul General of Argentina in Miami came to the medical campus last week to pay tribute to the consortium of researchers at Sylvester Comprehensive Cancer Center, the University of Miami Center for AIDS Research (CFAR) and institutions in Argentina that was awarded a prestigious National Cancer Institute U54 grant to study AIDS-related malignancies while developing the careers of junior researchers in Argentina.

Sylvester Researchers Recruiting Healthy Women for Ovarian Cancer Early Detection Study

01.17.2018

Often referred to as the “silent killer,” ovarian cancer does not become symptomatic for many women until a late stage of the disease. So any advance that shifts detection earlier, and allows physicians to intervene when survival remains potentially longer, can be welcome news. Sylvester researcher Brian Slomovitz, M.D., and colleagues are conducting a biomarker study to improve early detection, and survival.

Researchers Uncover Evidence of Early Genomic Aberrations in Uveal Melanoma

01.10.2018

Researchers from Sylvester Comprehensive Cancer Center and Bascom Palmer Eye Institute at the University of Miami Miller School of Medicine have uncovered evidence that genomic aberrations in uveal melanoma that lead to metastasis may occur far earlier in tumor evolution than previously believed. The findings fundamentally change the thinking about how this eye cancer progresses.