Stephen D. Nimer, M.D.

Sylvester Study Finds Potential New Approach to Treating Leukemia


A Miller School research study has found a potential new approach to halting the growth of acute myelogenous leukemia (AML), a deadly blood-borne cancer in adults and children. “We found that blocking an enzyme called PRMT4 caused leukemia cells to die,” said Stephen D. Nimer, M.D., Director of the Sylvester Comprehensive Cancer Center.

Ramiro E. Verdun, Ph.D.

Study Identifies DNA Repair Mechanism that Could Lead to Tumor-Targeted Treatment Strategies


In a study led by Ramiro E. Verdun, Ph.D., assistant professor of medicine in the Division of Gerontology and Geriatric Medicine, researchers have uncovered a mechanism to repair different types of DNA double-strand breaks, highly toxic lesions that, if left unrepaired, can produce a permanent arrest of cell division or cell death. These findings open the door to establishing new tumor-targeted treatment strategies.