News

Soumya Sundara Rajan, Ph.D., MSc, in the laboratory.

Novel Use of CRISPR for Cancer Research at Sylvester

12.20.2018

In Dr. Jonathan Schatz’s laboratory at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, researchers have pioneered a new use for CRISPR, the genomic editing tool at the center of much media attention.

At the Micah Batchelor Awards ceremony, from left, Henri R. Ford, M.D, MHA, Brent Pfeiffer, M.D., Ph.D., Merline Benny, M.D., Juan Solano, M.D., Asha Pillai, M.D., Judy Schaechter, M.D., MBA, and President Julio Frenk.

Four Researchers Honored by the Batchelor Foundation

12.14.2018

The 14th presentation of the Micah Batchelor Awards for Excellence in Children’s Health Research, created to recognize and inspire the development of innovative ideas and solutions to improve the health and well-being of children, took place November 8. Four researchers from Sylvester Comprehensive Cancer Center and the Department of Pediatrics at the University of Miami Miller School of Medicine were honored at the ceremony.

From left, Himanshu Arora, Ph.D., with Ranjith Ramasamy, M.D.

Sylvester Researchers Show Nitric Oxide Suppresses Drug-Resistant Prostate Cancer

10.15.2018

Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have shown in animal models that S-nitrosoglutathione (GSNO), a compound that increases nitric oxide (NO) levels, suppresses castration-resistant prostate cancer and has a major impact on tumor microenvironments. The discovery could lead to new therapies for prostate cancer patients with few options.

Carmen Calfa, M.D., right, talks to TAPUR Study participant Anita Shangvi and her daughter.

Sylvester is Sole Florida Site for TAPUR Study

09.26.2018

TAPUR — Targeted Agent and Profiling Utilization Registry — is for patients with advanced solid tumors in a variety of cancers, including breast, ovarian, pancreatic, and head and neck, which are no longer responding to standard cancer treatments.

Sylvester Comprehensive Cancer Center.

Florida Cancer Data System at Sylvester is Again Recognized as One of the Best in the U.S.

09.14.2018

The Florida Cancer Data System, the State of Florida’s legislatively mandated population-based registry located at Sylvester Comprehensive Cancer Center, has received three important distinctions for the quality of its cancer registry data. For the 16th consecutive year, the Florida Cancer Data System (FCDS) has received Gold Certification from the North American Association of Central Cancer Registries.

Sylvester Researchers Focus on an Interesting Target: PRMT5

09.04.2018

Cancer researchers spend a lot of time looking for good targets: potentially druggable molecules (mostly proteins) that affect cancer progression. The laboratory of Stephen D. Nimer, M.D., director of Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, has spent the past decade investigating an enzyme called PRMT5, which plays a role in leukemia, lymphoma and other cancers.

Sylvester Researchers Discover A Novel Mediator of Genome Instability Relevant to Many Cancers

08.27.2018

A research team at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine has discovered a novel role for a protein factor that allows it to contribute to the genome instability observed in many cancer cells. The investigators found that the FANCA protein plays an unexpected role in an error-prone DNA repair pathway that can drive the common instability mechanism.